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The antibody against POU3F1 was raised in rabbit using the Synthetic peptide of Human POU3F1 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
The antibody against POU3F1 was raised in rabbit using the Synthetic peptide of Human POU3F1 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
$299.00
| Cat.No | ADC-27586A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | POU3F1 |
| Form | Liquid | Species Reactivity | Human, Mouse, Rat |
| Isotype | IgG | Storage Buffer | 0.05% NaN3, 40% Glycerol., pH7.4 PBS |
| Purification Method | Antigen affinity purified | Conjugate | Non-conjugated |
| Application | ELISA, IHC | Storage | Upon receipt |
| Immunogen Description | Synthetic peptide of Human POU3F1 | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q03052 |
Uniprot Id
Q03052
Target Species
Human
Target Name
POU3F1
Target Full Name
POU domain, class 3, transcription factor 1
Target Function
Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3'). Acts as a transcriptional activator when binding cooperatively with SOX4, SOX11, or SOX12 to gene promoters. Acts as a transcriptional repressor of myelin-specific genes.
Target Subcellular Location
Nucleus.
Target Protein Families
POU transcription factor family, Class-3 subfamily
Target Tissue Specificity
Expressed in embryonal stem cells and in the developing brain.
Target Synonyms
OCT6; OTF6; SCIP; POU3F1
Target Background
Enables sequence-specific double-stranded DNA binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II; positive regulation of gene expression; and positive regulation of transcription, DNA-templated. Predicted to act upstream of or within keratinocyte differentiation; nervous system development; and positive regulation of transcription by RNA polymerase II. Located in nucleoplasm.
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