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The antibody against PTDSS1 was raised in rabbit using the Recombinant Human Phosphatidylserine synthase 1 protein (1-35AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC, IF.
The antibody against PTDSS1 was raised in rabbit using the Recombinant Human Phosphatidylserine synthase 1 protein (1-35AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC, IF.
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Immunohistochemistry of paraffin-embedded human liver tissue using PTDSS1 Antibody at dilution of 1:1002
| Cat.No | ADC-54382A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | PTDSS1 |
| Target Synonyms | PTDSS1 antibody; KIAA0024 antibody; PSSA antibody; Phosphatidylserine synthase 1 antibody; PSS-1 antibody; PtdSer synthase 1 antibody; EC 2.7.8.29 antibody; Serine-exchange enzyme I antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, IF, IHC, WB |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Phosphatidylserine synthase 1 protein (1-35AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P48651 |
Uniprot Id
P48651
Target Species
Human
Target Name
PTDSS1
Target Full Name
Phosphatidylserine synthase 1
Target Function
Catalyzes a base-exchange reaction in which the polar head group of phosphatidylethanolamine (PE) or phosphatidylcholine (PC) is replaced by L-serine. Catalyzes mainly the conversion of phosphatidylcholine. Also converts, in vitro and to a lesser extent, phosphatidylethanolamine.
Target Involvement
Lenz-Majewski hyperostotic dwarfism (LMHD)
Target Subcellular Location
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Target Protein Families
Phosphatidyl serine synthase family
Target Research Area
Metabolism
Target Synonyms
PTDSS1; KIAA0024; PSSA; Phosphatidylserine synthase 1; PSS-1; PtdSer synthase 1; EC 2.7.8.29; Serine-exchange enzyme I
Target Background
The protein encoded by this gene catalyzes the formation of phosphatidylserine from either phosphatidylcholine or phosphatidylethanolamine. Phosphatidylserine localizes to the mitochondria-associated membrane of the endoplasmic reticulum, where it serves a structural role as well as a signaling role. Defects in this gene are a cause of Lenz-Majewski hyperostotic dwarfism. Two transcript variants encoding different isoforms have been found for this gene.
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