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Rabbit anti-Human PTH Polyclonal Antibody

The antibody against PTH was raised in rabbit using the Human PTH-Specific as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.

ADC-51181A

The antibody against PTH was raised in rabbit using the Human PTH-Specific as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.

$600.00

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Specifications


Cat.No ADC-51181A ClonalityPolyclonal
Host SpeciesRabbitTarget Namepth
FormLiquidSpecies ReactivityHuman
IsotypeIgGStorage Buffer50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.02% sodium azide
Purification MethodAntigen affinity purifiedConjugateNon-conjugated
ApplicationELISA, WBStorageUpon receipt

Immunogen Information


Immunogen DescriptionHuman PTH-SpecificTarget SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDP01270
Background Information
  • Uniprot Id

    P01270

  • Target Species

    Human

  • Target Name

    PTH

  • Target Full Name

    Parathyroid hormone

  • Target Function

    PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion. Stimulates [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblastic cells.

  • Target Involvement

    Hypoparathyroidism, familial isolated (FIH)

  • Target Subcellular Location

    Secreted.

  • Target Protein Families

    Parathyroid hormone family

  • Target Synonyms

    FIH1; PTH1; Parathyroid Hormone (PTH)

  • Target Background

    This gene encodes a member of the parathyroid family of proteins. The encoded preproprotein is proteolytically processed to generate a protein that binds to the parathyroid hormone/parathyroid hormone-related peptide receptor and regulates blood calcium and phosphate levels. Excess production of the encoded protein, known as hyperparathyroidism, can result in hypercalcemia and kidney stones. On the other hand, defective processing of the encoded protein may lead to hypoparathyroidism, which can result in hypocalcemia and numbness. Alternative splicing results in multiple transcript variants.

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