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Rabbit anti-Human PTPN5 Polyclonal Antibody

The antibody against PTPN5 was raised in rabbit using the Fusion protein of Human PTPN5 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.

ADC-29463A

The antibody against PTPN5 was raised in rabbit using the Fusion protein of Human PTPN5 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.

$299.00

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Specifications


Cat.No ADC-29463A ClonalityPolyclonal
Host SpeciesRabbitTarget NamePTPN5
FormLiquidSpecies ReactivityHuman, Mouse, Rat
IsotypeIgGStorage Buffer0.05% NaN3, 40% Glycerol., pH7.4 PBS
Purification MethodAntigen affinity purifiedConjugateNon-conjugated
ApplicationELISA, IHCStorageUpon receipt

Immunogen Information


Immunogen DescriptionFusion protein of Human PTPN5Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDP54829
Background Information
  • Uniprot Id

    P54829

  • Target Species

    Human

  • Target Name

    PTPN5

  • Target Full Name

    Tyrosine-protein phosphatase non-receptor type 5

  • Target Function

    May regulate the activity of several effector molecules involved in synaptic plasticity and neuronal cell survival, including MAPKs, Src family kinases and NMDA receptors.

  • Target Subcellular Location

    Endoplasmic reticulum membrane; Multi-pass membrane protein.

  • Target Protein Families

    Protein-tyrosine phosphatase family, Non-receptor class subfamily

  • Target Synonyms

    FLJ14427; Neural specific protein tyrosine phosphatase; Neural-specific protein-tyrosine phosphatase; Protein tyrosine phosphatase non receptor type 5 (striatum enriched); Protein tyrosine phosphatase non receptor type 5; Protein tyrosine phosphatase striatum enriched; PTN5; PTN5_HUMAN; PTP STEP; PTPN 5; Ptpn5; PTPSTEP; STEP; Striatum-enriched protein-tyrosine phosphatase; Tyrosine protein phosphatase non receptor type 5; Tyrosine-protein phosphatase non-receptor type 5

  • Target Background

    Enables phosphotyrosine residue binding activity. Predicted to be involved in peptidyl-tyrosine dephosphorylation. Predicted to act upstream of or within protein dephosphorylation. Predicted to be located in nucleoplasm. Predicted to be integral component of membrane. Biomarker of Alzheimer's disease.

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