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Rabbit anti-Human PXK Polyclonal Antibody

The antibody against PXK was raised in rabbit using the Recombinant Human PX domain-containing protein kinase-like protein (1-200AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC.

ADC-09833A

The antibody against PXK was raised in rabbit using the Recombinant Human PX domain-containing protein kinase-like protein (1-200AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC.

$299.00

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Specifications


Cat.No ADC-09833A ClonalityPolyclonal
Host SpeciesRabbitTarget NamePXK
FormLiquidSpecies ReactivityHuman, Mouse, Rat
IsotypeIgGStorage Buffer0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4
Purification Method>95%, Protein G purifiedConjugateNon-conjugated
ApplicationELISA, IHC, WBStorageUpon receipt

Immunogen Information


Immunogen DescriptionRecombinant Human PX domain-containing protein kinase-like protein (1-200AA)Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ7Z7A4
Background Information
  • Uniprot Id

    Q7Z7A4

  • Target Species

    Human

  • Target Name

    PXK

  • Target Full Name

    PX domain-containing protein kinase-like protein

  • Target Function

    Binds to and modulates brain Na,K-ATPase subunits ATP1B1 and ATP1B3 and may thereby participate in the regulation of electrical excitability and synaptic transmission. May not display kinase activity.

  • Target Subcellular Location

    Cytoplasm. Cell membrane; Peripheral membrane protein. Note=Also associates with the plasma membrane. Isoform 3 is present throughout the cell.

  • Target Protein Families

    Protein kinase superfamily

  • Target Tissue Specificity

    Widely expressed in all tissues examined except in heart. Isoform 1 is expressed in high levels in the brain, skeletal muscle, spleen and testis. Isoform 7 expression has yet to be demonstrated.

  • Target Synonyms

    FLJ20335; K-ATPase; Modulator of Na; Modulator of Na K ATPase ; Modulator of Na K ATPase long form ; MONaKA; PX domain containing protein kinase like protein ; PX domain containing serine/threonine kinase ; PX domain-containing protein kinase-like protein; PX ser/thr kinase v2 ; PX serine/threonine kinase ; Pxk; PXK_HUMAN

  • Target Background

    This gene encodes a phox (PX) domain-containing protein which may be involved in synaptic transmission and the ligand-induced internalization and degradation of epidermal growth factors. Variations in this gene may be associated with susceptibility to systemic lupus erythematosus (SLE). Alternative splicing results in multiple transcript variants.

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