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The antibody against RAP2A was raised in rabbit using the Human RAP2A as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.
The antibody against RAP2A was raised in rabbit using the Human RAP2A as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.
$600.00
| Cat.No | ADC-47412A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | RAP2A |
| Target Synonyms | RAP2A antibody; Ras-related protein Rap-2a antibody; RbBP-30 antibody | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.02% sodium azide | Purification Method | Antigen affinity purified |
| Conjugate | Non-conjugated | Application | ELISA, WB |
| Storage | Upon receipt |
| Immunogen Description | Human RAP2A | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P10114 |
Uniprot Id
P10114
Target Species
Human
Target Name
RAP2A
Target Full Name
Ras-related protein Rap-2a
Target Function
Small GTP-binding protein which cycles between a GDP-bound inactive and a GTP-bound active form. In its active form interacts with and regulates several effectors including MAP4K4, MINK1 and TNIK. Part of a signaling complex composed of NEDD4, RAP2A and TNIK which regulates neuronal dendrite extension and arborization during development. More generally, it is part of several signaling cascades and may regulate cytoskeletal rearrangements, cell migration, cell adhesion and cell spreading.
Target Subcellular Location
Recycling endosome membrane; Lipid-anchor; Cytoplasmic side. Midbody.
Target Protein Families
Small GTPase superfamily, Ras family
Target Synonyms
RAP2A; Ras-related protein Rap-2a; RbBP-30
Target Background
Enables GTPase activity; guanyl ribonucleotide binding activity; and magnesium ion binding activity. Involved in several processes, including actin cytoskeleton reorganization; microvillus assembly; and positive regulation of protein autophosphorylation. Acts upstream of or within establishment of protein localization. Located in plasma membrane and recycling endosome membrane.
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