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The antibody against REG3G was raised in rabbit using the Recombinant Human Regenerating islet-derived protein 3-gamma protein (27-175AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.
The antibody against REG3G was raised in rabbit using the Recombinant Human Regenerating islet-derived protein 3-gamma protein (27-175AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.
$299.00
| Cat.No | ADC-25344A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | REG3G |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Regenerating islet-derived protein 3-gamma protein (27-175AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q6UW15 |
Uniprot Id
Q6UW15
Target Species
Human
Target Name
REG3G
Target Full Name
Regenerating islet-derived protein 3-gamma
Target Function
Bactericidal C-type lectin which acts exclusively against Gram-positive bacteria and mediates bacterial killing by binding to surface-exposed carbohydrate moieties of peptidoglycan. Restricts bacterial colonization of the intestinal epithelial surface and consequently limits activation of adaptive immune responses by the microbiota. The uncleaved form has bacteriostatic activity, whereas the cleaved form has bactericidal activity against L.monocytogenes and methicillin-resistant S.aureus. Regulates keratinocyte proliferation and differentiation after skin injury.
Target Subcellular Location
Secreted. Cytoplasm.
Target Tissue Specificity
Predominantly expressed in pancreas, where it may be restricted to exocrine pancreas. Moderate expression levels in testis and weak in heart, kidney and placenta.
Target Research Area
Immunology
Target Synonyms
LPPM429; Pancreatitis-associated protein 1B; Pancreatitis-associated protein IB; PAP IB; PAP-1B; PAP1B; PAPIB; REG III; Reg III-gamma; REG-3-gamma; REG3G; REG3G_HUMAN; Regenerating islet derived 3 gamma; Regenerating islet-derived protein 3-gamma; Regenerating islet-derived protein III-gamma; UNQ429
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