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The antibody against RFTN1 was raised in rabbit using the Synthesized peptide derived from the C-terminal region of Human Raftlin. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, ELISA.
The antibody against RFTN1 was raised in rabbit using the Synthesized peptide derived from the C-terminal region of Human Raftlin. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, ELISA.
$167.00
Western Blot analysis of 3T3 cells using Raftlin Polyclonal Antibody
| Cat.No | ADC-35827A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | RFTN1 |
| Target Synonyms | RFTN1 antibody; KIAA0084 antibody; MIG2 antibody; Raftlin antibody; Cell migration-inducing gene 2 protein antibody; Raft-linking protein antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.5% BSA and 0.02% sodium azide., Liquid in PBS containing 50% glycerol | Purification Method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Conjugate | Non-conjugated | Application | ELISA, WB |
| Storage | Upon receipt |
| Immunogen Description | Synthesized peptide derived from the C-terminal region of Human Raftlin. | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q14699 |
Uniprot Id
Q14699
Target Species
Human
Target Name
RFTN1
Target Full Name
Raftlin
Target Function
Involved in protein trafficking via association with clathrin and AP2 complex. Upon bacterial lipopolysaccharide stimulation, mediates internalization of TLR4 to endosomes in dendritic cells and macrophages; and internalization of poly(I:C) to TLR3-positive endosomes in myeloid dendritic cells and epithelial cells; resulting in activation of TICAM1-mediated signaling and subsequent IFNB1 production. Involved in T-cell antigen receptor-mediated signaling by regulating tyrosine kinase LCK localization, T-cell dependent antibody production and cytokine secretion. May regulate B-cell antigen receptor-mediated signaling. May play a pivotal role in the formation and/or maintenance of lipid rafts.
Target Subcellular Location
Cell membrane; Lipid-anchor. Cytoplasm. Membrane raft. Endosome. Early endosome.
Target Protein Families
Raftlin family
Target Tissue Specificity
Expressed in B-cells (at protein level). Expressed in dendritic cells and macrophages.
Target Synonyms
RFTN1; KIAA0084; MIG2; Raftlin; Cell migration-inducing gene 2 protein; Raft-linking protein
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