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The antibody against RGS7 was raised in rabbit using the Recombinant Human Regulator of G-protein signaling 7 protein (1-487AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
The antibody against RGS7 was raised in rabbit using the Recombinant Human Regulator of G-protein signaling 7 protein (1-487AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
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Immunohistochemistry of paraffin-embedded human brain tissue using RGS7 Antibody at dilution of 1:100
Immunohistochemistry of paraffin-embedded human colon cancer using RGS7 Antibody at dilution of 1:1002
| Cat.No | ADC-23842A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | RGS7 |
| Target Synonyms | RGS7 antibody; Regulator of G-protein signaling 7 antibody; RGS7 antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, IHC |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Regulator of G-protein signaling 7 protein (1-487AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P49802 |
Uniprot Id
P49802
Target Species
Human
Target Name
RGS7
Target Full Name
Regulator of G-protein signaling 7
Target Function
Regulates G protein-coupled receptor signaling cascades. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form. The RGS7/GNB5 dimer enhances GNAO1 GTPase activity. May play a role in synaptic vesicle exocytosis. Modulates the activity of potassium channels that are activated by GNAO1 in response to muscarinic acetylcholine receptor M2/CHRM2 signaling.
Target Subcellular Location
Cytoplasm, cytosol. Cytoplasm. Cell membrane. Membrane; Peripheral membrane protein; Cytoplasmic side.
Target Research Area
Signal Transduction
Target Synonyms
RGS7; Regulator of G-protein signaling 7; RGS7
Target Background
Enables G-protein beta-subunit binding activity and GTPase activator activity. Involved in positive regulation of GTPase activity. Located in cytosol.
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