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The antibody against RHD was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 150-250 of human RHD (NP_001121163.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against RHD was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 150-250 of human RHD (NP_001121163.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-05278A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | RHD |
| Target Synonyms | RH; Rh4; RH30; RhII; RhPI; DIIIc; RHCED; RHDel; RHPII; RhDCw; CD240D; HDFNRH; RHXIII; RHDVA(TT); RhK562-II; RHD | Form | Liquid |
| Species Reactivity | Human, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | LO2, Rat liver, Rat spleen, U-251MG | Application | ELISA, WB |
| Immunogen Description | A synthetic peptide corresponding to a sequence within amino acids 150-250 of human RHD (NP_001121163.1). | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | LGNLRMVISNIFNTDYHMNMMHIYVFAAYFGLSVAWCLPKPLPEGTEDKDQTATIPSLSAMLGALFLWMFWPSFNSALLRSPIERKNAVFNTYYAVAVSVV | Uniprot ID | Q02161 |
Uniprot Id
Q02161
Target Species
Human
Target Name
RHD
Target Full Name
Blood group Rh(D) polypeptide
Target Function
May be part of an oligomeric complex which is likely to have a transport or channel function in the erythrocyte membrane.
Target Subcellular Location
Cell membrane; Multi-pass membrane protein.
Target Protein Families
Ammonium transporter (TC 2.A.49) family, Rh subfamily
Target Tissue Specificity
Restricted to tissues or cell lines expressing erythroid characters.
Target Research Area
Cardiovascular
Target Synonyms
RHD; Blood group Rh(D polypeptide; RHXIII; Rh polypeptide 2; RhPII; Rhesus D antigen; CD antigen CD240D
Target Background
The Rh blood group system is the second most clinically significant of the blood groups, second only to ABO. It is also the most polymorphic of the blood groups, with variations due to deletions, gene conversions, and missense mutations. The Rh blood group includes this gene, which encodes the RhD protein, and a second gene that encodes both the RhC and RhE antigens on a single polypeptide. The two genes, and a third unrelated gene, are found in a cluster on chromosome 1. The classification of Rh-positive and Rh-negative individuals is determined by the presence or absence of the highly immunogenic RhD protein on the surface of erythrocytes. Multiple transcript variants encoding different isoforms have been found for this gene.
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