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The antibody against RIC1 was raised in rabbit using the Recombinant Human RAB6A-GEF complex partner protein 1 protein (951-1233AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
The antibody against RIC1 was raised in rabbit using the Recombinant Human RAB6A-GEF complex partner protein 1 protein (951-1233AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
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Immunohistochemistry of paraffin-embedded human pancreatic cancer using RIC1 Antibody at dilution of 1:100
Immunofluorescent analysis of HepG2 cells using RIC1 Antibody at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)2
| Cat.No | ADC-15397A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | RIC1 |
| Target Synonyms | Connexin-43-interacting protein of 150 kDa antibody; Kiaa1432 antibody; Protein RIC1 homolog antibody; RIC1_HUMAN antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, IF, IHC |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human RAB6A-GEF complex partner protein 1 protein (951-1233AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q4ADV7 |
Uniprot Id
Q4ADV7
Target Species
Human
Target Name
RIC1
Target Full Name
Guanine nucleotide exchange factor subunit RIC1
Target Function
The RIC1-RGP1 complex acts as a guanine nucleotide exchange factor (GEF), which activates RAB6A by exchanging bound GDP for free GTP, and may thereby be required for efficient fusion of endosome-derived vesicles with the Golgi compartment. The RIC1-RGP1 complex participates in the recycling of mannose-6-phosphate receptors. Required for phosphorylation and localization of GJA1. Is a regulator of procollagen transport and secretion, and is required for correct cartilage morphogenesis and development of the craniofacial skeleton.
Target Subcellular Location
Cytoplasm, cytosol. Membrane.
Target Protein Families
RIC1 family
Target Tissue Specificity
Present in kidney and various cell lines (at protein level). Widely expressed at low level.
Target Synonyms
Connexin-43-interacting protein of 150 kDa; Kiaa1432; Protein RIC1 homolog; RIC1_HUMAN
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