Rabbit anti-Human RLN1 Polyclonal Antibody

The antibody against RLN1 was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 1-100 of human RLN1 (NP_008842.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-04888A

Number

Cat.No	ADA-04888A	Clonality	Polyclonal
Host Species	Rabbit	Target Name	RLN1
Target Synonyms	H1; H1RLX; RLXH1; bA12D24.3.1; bA12D24.3.2; RLN1	Form	Liquid
Species Reactivity	Human	Isotype	IgG
Storage Buffer	50% Glycerol, PBS with 0.01% thimerosal, pH7.3.	Purification Method	Affinity purification
Positive Samples	22Rv1	Application	ELISA, WB

Cat.No

ADA-04888A

Clonality

Polyclonal

Host Species

Rabbit

Target Name

RLN1

Target Synonyms

H1; H1RLX; RLXH1; bA12D24.3.1; bA12D24.3.2; RLN1

Form

Liquid

Species Reactivity

Human

Isotype

IgG

Storage Buffer

50% Glycerol, PBS with 0.01% thimerosal, pH7.3.

Purification Method

Affinity purification

Positive Samples

22Rv1

Application

ELISA, WB

Immunogen Description	A synthetic peptide corresponding to a sequence within amino acids 1-100 of human RLN1 (NP_008842.1).	Target Species	Human
Immunogen Sequence	MPRLFLFHLLEFCLLLNQFSRAVAAKWKDDVIKLCGRELVRAQIAICGMSTWSKRSLSQEDAPQTPRPVAEIVPSFINKDTETIIIMLEFIANLPPELKA	Uniprot ID	P04808

Immunogen Description

A synthetic peptide corresponding to a sequence within amino acids 1-100 of human RLN1 (NP_008842.1).

Target Species

Human

Immunogen Sequence

MPRLFLFHLLEFCLLLNQFSRAVAAKWKDDVIKLCGRELVRAQIAICGMSTWSKRSLSQEDAPQTPRPVAEIVPSFINKDTETIIIMLEFIANLPPELKA

Uniprot ID

P04808

Background Information

Uniprot Id

P04808
Target Species

Human
Target Name

RLN1
Target Full Name

Prorelaxin H1
Target Function

Relaxin is an ovarian hormone that acts with estrogen to produce dilatation of the birth canal in many mammals. May be involved in remodeling of connective tissues during pregnancy, promoting growth of pubic ligaments and ripening of the cervix.
Target Subcellular Location

Secreted.
Target Protein Families

Insulin family
Target Tissue Specificity

Prostate. Not expressed in placenta, decidua or ovary.
Target Synonyms

H1; H1RLX; Preprorelaxin H1; Prorelaxin; Prorelaxin H1; REL1_HUMAN; Relaxin A chain; Relaxin H1; RLN 1; Rln1; RLXH1
Target Background

Relaxins are known endocrine and autocrine/paracrine hormones, belonging to the insulin gene superfamily. In humans there are three non-allelic relaxin genes, RLN1, RLN2 and RLN3, where RLN1 and RLN2 share high sequence homology. The protein encoded by this gene is synthesized as a single-chain polypeptide but the active form consists of an A chain and a B chain linked by disulfide bonds. Relaxin is produced by the ovary, and targets the mammalian reproductive system to ripen the cervix, elongate the pubic symphysis and inhibit uterine contraction. It may have additional roles in enhancing sperm motility, regulating blood pressure, controlling heart rate and releasing oxytocin and vasopressin.

Rabbit anti-Human RLN1 Polyclonal Antibody

Specifications

Immunogen Information

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