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The antibody against RNF213 was raised in rabbit using the Recombinant Human E3 ubiquitin-protein ligase RNF213 protein (202-350AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
The antibody against RNF213 was raised in rabbit using the Recombinant Human E3 ubiquitin-protein ligase RNF213 protein (202-350AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
$299.00
| Cat.No | ADC-06591A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | RNF213 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IF, IHC | Storage | Upon receipt |
| Immunogen Description | Recombinant Human E3 ubiquitin-protein ligase RNF213 protein (202-350AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q63HN8 |
Uniprot Id
Q63HN8
Target Species
Human
Target Name
RNF213
Target Full Name
E3 ubiquitin-protein ligase RNF213
Target Function
E3 ubiquitin-protein ligase involved in angiogenesis. Involved in the non-canonical Wnt signaling pathway in vascular development: acts by mediating ubiquitination and degradation of FLNA and NFATC2 downstream of RSPO3, leading to inhibit the non-canonical Wnt signaling pathway and promoting vessel regression. Also has ATPase activity.
Target Involvement
Moyamoya disease 2 (MYMY2)
Target Subcellular Location
Cytoplasm, cytosol.
Target Protein Families
AAA ATPase family
Target Tissue Specificity
Widely expressed (at protein level).
Target Synonyms
ALK lymphoma oligomerization partner on chromosome 17; C17orf27; Chromosome 17 open reading frame 27; E3 ubiquitin-protein ligase RNF213; FLJ13051; KIAA1554; MGC46622; MGC9929; MYMY2; Mysterin; MYSTR; NET57; RING finger protein 213; RN213_HUMAN; RNF 213; RNF213
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