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The antibody against RNF220 was raised in rabbit using the Recombinant Human E3 ubiquitin-protein ligase RNF220 protein (384-472AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
The antibody against RNF220 was raised in rabbit using the Recombinant Human E3 ubiquitin-protein ligase RNF220 protein (384-472AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
$299.00
| Cat.No | ADC-04059A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | RNF220 |
| Target Synonyms | RNF220 antibody; C1orf164 antibody; E3 ubiquitin-protein ligase RNF220 antibody; EC 2.3.2.27 antibody; RING finger protein 220 antibody; RING-type E3 ubiquitin transferase RNF220 antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, IHC |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human E3 ubiquitin-protein ligase RNF220 protein (384-472AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q5VTB9 |
Uniprot Id
Q5VTB9
Target Species
Human
Target Name
RNF220
Target Full Name
E3 ubiquitin-protein ligase RNF220
Target Function
E3 ubiquitin-protein ligase that promotes the ubiquitination and proteasomal degradation of SIN3B. Independently of its E3 ligase activity, acts as a CTNNB1 stabilizer through USP7-mediated deubiquitination of CTNNB1 promoting Wnt signaling.
Target Subcellular Location
Cytoplasm.
Target Synonyms
RNF220; C1orf164; E3 ubiquitin-protein ligase RNF220; EC 2.3.2.27; RING finger protein 220; RING-type E3 ubiquitin transferase RNF220
Target Background
Predicted to enable ubiquitin protein ligase activity. Involved in positive regulation of canonical Wnt signaling pathway. Part of protein-containing complex.
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