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The antibody against ROBO2 was raised in rabbit using the Synthetic peptide of Human ROBO2 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
The antibody against ROBO2 was raised in rabbit using the Synthetic peptide of Human ROBO2 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
$299.00
| Cat.No | ADC-26020A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | ROBO2 |
| Target Synonyms | axon guidance receptor, homolog 2 (Drosophila) antibody; Roundabout2 antibody; SAX 3 antibody; SAX3 antibody, lea antibody; Robo 2 antibody; Robo2 antibody; ROBO2_HUMAN antibody; Roundabout 2 antibody; Roundabout homolog 2 antibody; roundabout | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.05% NaN3, 40% Glycerol., pH7.4 PBS | Purification Method | Antigen affinity purified |
| Conjugate | Non-conjugated | Application | ELISA, IHC |
| Storage | Upon receipt |
| Immunogen Description | Synthetic peptide of Human ROBO2 | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9HCK4 |
Uniprot Id
Q9HCK4
Target Species
Human
Target Name
ROBO2
Target Full Name
Roundabout homolog 2
Target Function
Receptor for SLIT2, and probably SLIT1, which are thought to act as molecular guidance cue in cellular migration, including axonal navigation at the ventral midline of the neural tube and projection of axons to different regions during neuronal development.
Target Involvement
Vesicoureteral reflux 2 (VUR2)
Target Subcellular Location
Membrane; Single-pass type I membrane protein.
Target Protein Families
Immunoglobulin superfamily, ROBO family
Target Synonyms
lea; Robo 2; Robo2; ROBO2_HUMAN; Roundabout 2; Roundabout homolog 2; roundabout, axon guidance receptor, homolog 2 (Drosophila); Roundabout2; SAX 3; SAX3
Target Background
The protein encoded by this gene belongs to the ROBO family, part of the immunoglobulin superfamily of proteins that are highly conserved from fly to human. The encoded protein is a transmembrane receptor for the slit homolog 2 protein and functions in axon guidance and cell migration. Mutations in this gene are associated with vesicoureteral reflux, characterized by the backward flow of urine from the bladder into the ureters or the kidney. Alternative splicing results in multiple transcript variants.
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