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The antibody against SACS was raised in rabbit using the Recombinant Human Sacsin protein (983-1150AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
The antibody against SACS was raised in rabbit using the Recombinant Human Sacsin protein (983-1150AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
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Immunohistochemistry of paraffin-embedded human brain tissue using SACS Antibody at dilution of 1:100
Immunohistochemistry of paraffin-embedded human placenta tissue using SACS Antibody at dilution of 1:1002
| Cat.No | ADC-08999A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | SACS |
| Target Synonyms | DnaJ homolog subfamily C member 29 antibody; DNAJC29 antibody; SACS antibody; SACS_HUMAN antibody; Sacsin antibody; Spastic ataxia of Charlevoix-Saguenay antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, IF, IHC |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Sacsin protein (983-1150AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9NZJ4 |
Uniprot Id
Q9NZJ4
Target Species
Human
Target Name
SACS
Target Full Name
Sacsin
Target Function
Co-chaperone which acts as a regulator of the Hsp70 chaperone machinery and may be involved in the processing of other ataxia-linked proteins.
Target Involvement
Spastic ataxia Charlevoix-Saguenay type (SACS)
Target Subcellular Location
Cytoplasm. Note=Predominantly cytoplasmic, a small portion is present in the nucleus and also shows a partial mitochondrial overlap with the mitochondrial marker Hsp60.
Target Tissue Specificity
Highly expressed in the central nervous system. Also found in skeletal muscle and at low levels in pancreas.
Target Synonyms
DnaJ homolog subfamily C member 29; DNAJC29; SACS; SACS_HUMAN; Sacsin; Spastic ataxia of Charlevoix-Saguenay
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