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The antibody against SCUBE2 was raised in rabbit using the Recombinant Human Signal peptide, CUB and EGF-like domain-containing protein 2 protein (534-703AA) as the immunogen. This antibody exists as a hrp conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.
The antibody against SCUBE2 was raised in rabbit using the Recombinant Human Signal peptide, CUB and EGF-like domain-containing protein 2 protein (534-703AA) as the immunogen. This antibody exists as a hrp conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.
$299.00
| Cat.No | ADC-06350A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | SCUBE2 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | HRP conjugated |
| Application | ELISA | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Signal peptide, CUB and EGF-like domain-containing protein 2 protein (534-703AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9NQ36 |
Uniprot Id
Q9NQ36
Target Species
Human
Target Name
SCUBE2
Target Full Name
Signal peptide, CUB and EGF-like domain-containing protein 2
Target Function
Lipid-binding protein required for SHH long-range signaling by binding to the dually lipid-modified SHH (ShhNp) and by promoting ShhNp mobilization, solubilization and release from the cell membrane. Acts by enhancing the proteolytic processing (shedding) of the lipid-modified N- and C- terminal of ShhNp at the cell surface. Synergizes with DISP1 to increase SHH secretion. Probable cell surface coreceptor for VEGFR2 involved in VEGFR2-mediated angiogenesis.
Target Subcellular Location
Secreted. Cell surface.
Target Tissue Specificity
Expressed in a broad spectrum of adult tissues.
Target Synonyms
4932442O19Rik; Cegb1; Cegf1; CEGP1; Cegp1 protein; CUB domain and EGF-like repeat containing 1; FLJ16792; FLJ35234; ICRFP703B1614Q5.1; MGC133057; Protein CEGP1; RGD1563998; SCUB2_HUMAN; Scube2; Signal peptide; CUB and EGF-like domain-containing protein 2; Signal peptide; CUB domain; EGF-like 2
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