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Rabbit anti-Human SEC23IP Polyclonal Antibody

The antibody against SEC23IP was raised in rabbit using the Human SEC23IP as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.

ADC-51933A

The antibody against SEC23IP was raised in rabbit using the Human SEC23IP as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.

$600.00

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Specifications


Cat.No ADC-51933A ClonalityPolyclonal
Host SpeciesRabbitTarget NameSEC23IP
Target SynonymsMSTP053 antibody; p125 antibody; P125A antibody; Phospholipase antibody; S23IP_HUMAN antibody; Sec23 interacting protein p125 antibody; SEC23-interacting protein antibody; SEC23IP antibodyFormLiquid
Species ReactivityHuman, Mouse, RatIsotypeIgG
Storage Buffer50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.02% sodium azidePurification MethodAntigen affinity purified
ConjugateNon-conjugatedApplicationELISA, WB
StorageUpon receipt

Immunogen Information


Immunogen DescriptionHuman SEC23IPTarget SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ9Y6Y8
Background Information
  • Uniprot Id

    Q9Y6Y8

  • Target Species

    Human

  • Target Name

    SEC23IP

  • Target Full Name

    SEC23-interacting protein

  • Target Function

    Plays a role in the organization of endoplasmic reticulum exit sites. Specifically binds to phosphatidylinositol 3-phosphate (PI(3)P), phosphatidylinositol 4-phosphate (PI(4)P) and phosphatidylinositol 5-phosphate (PI(5)P).

  • Target Subcellular Location

    Cytoplasmic vesicle, COPII-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Endoplasmic reticulum.

  • Target Protein Families

    PA-PLA1 family

  • Target Tissue Specificity

    Ubiquitously expressed with stronger levels detected in heart, liver and skeletal muscle.

  • Target Synonyms

    MSTP053; p125; P125A; Phospholipase; S23IP_HUMAN; Sec23 interacting protein p125; SEC23-interacting protein; SEC23IP

  • Target Background

    This gene encodes a member of the phosphatidic acid preferring-phospholipase A1 family. The encoded protein is localized to endoplasmic reticulum exit sites and plays a critical role in ER-Golgi transport as part of the multimeric coat protein II complex. An orthologous gene in frogs is required for normal neural crest cell development, suggesting that this gene may play a role in Waardenburg syndrome neural crest defects. Alternatively spliced transcript variants have been observed for this gene.

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