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The antibody against SLC24A5 was raised in rabbit using the Recombinant Human Sodium/potassium/calcium exchanger 5 protein (240-298AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB.
The antibody against SLC24A5 was raised in rabbit using the Recombinant Human Sodium/potassium/calcium exchanger 5 protein (240-298AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB.
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| Cat.No | ADC-10341A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | SLC24A5 |
| Target Synonyms | member 5 antibody, member 5 antibody; Solute carrier family 24 member 5 antibody; Solute carrier family 24 | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, WB |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Sodium/potassium/calcium exchanger 5 protein (240-298AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q71RS6 |
Uniprot Id
Q71RS6
Target Species
Human
Target Name
SLC24A5
Target Full Name
Sodium/potassium/calcium exchanger 5
Target Function
Cation exchanger involved in pigmentation, possibly by participating in ion transport in melanosomes. Predominant sodium-Calcium exchanger in melanocytes. Probably transports 1 Ca(2+) and 1 K(+) to the melanosome in exchange for 4 cytoplasmic Na(+).
Target Involvement
Albinism, oculocutaneous, 6 (OCA6)
Target Subcellular Location
Golgi apparatus, trans-Golgi network membrane; Multi-pass membrane protein. Melanosome. Note=Enriched in late-stage melanosomes (PubMed:17081065).
Target Protein Families
Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family, SLC24A subfamily
Target Synonyms
Ion transporter JSX; JSX; Na(+)/K(+)/Ca(2+)-exchange protein 5; NCKX5; NCKX5_HUMAN; Slc24a5; Sodium/potassium/calcium exchanger 5; Solute carrier family 24 (sodium/potassium/calcium exchanger),member 5; Solute carrier family 24 member 5; Solute carrier family 24,member 5
Target Background
This gene is a member of the potassium-dependent sodium/calcium exchanger family and encodes an intracellular membrane protein with 2 large hydrophilic loops and 2 sets of multiple transmembrane-spanning segments. Sequence variation in this gene has been associated with differences in skin pigmentation.
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