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Rabbit anti-Human SLC25A11 Polyclonal Antibody

The antibody against SLC25A11 was raised in rabbit using the Fusion protein of Human SLC25A11 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.

ADC-31374A

The antibody against SLC25A11 was raised in rabbit using the Fusion protein of Human SLC25A11 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.

$299.00

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Specifications


Cat.No ADC-31374A ClonalityPolyclonal
Host SpeciesRabbitTarget NameSLC25A11
Target SynonymsSLC25A11; SLC20A4; Mitochondrial 2-oxoglutarate/malate carrier protein; OGCP; Solute carrier family 25 member 11FormLiquid
Species ReactivityHuman, Mouse, RatIsotypeIgG
Storage Buffer0.05% NaN3, 40% Glycerol., pH7.4 PBSPurification MethodAntigen affinity purified
ConjugateNon-conjugatedApplicationELISA, IHC, WB
StorageUpon receipt

Immunogen Information


Immunogen DescriptionFusion protein of Human SLC25A11Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ02978
Background Information
  • Uniprot Id

    Q02978

  • Target Species

    Human

  • Target Name

    SLC25A11

  • Target Full Name

    Mitochondrial 2-oxoglutarate/malate carrier protein

  • Target Function

    Catalyzes the transport of 2-oxoglutarate across the inner mitochondrial membrane in an electroneutral exchange for malate or other dicarboxylic acids, and plays an important role in several metabolic processes, including the malate-aspartate shuttle, the oxoglutarate/isocitrate shuttle, in gluconeogenesis from lactate, and in nitrogen metabolism. Maintains mitochondrial fusion and fission events, and the organization and morphology of cristae. Involved in the regulation of apoptosis. Acts as a tumor-suppressor gene implicated in the predisposition to metastatic paraganglioma.

  • Target Subcellular Location

    Mitochondrion inner membrane; Multi-pass membrane protein.

  • Target Protein Families

    Mitochondrial carrier (TC 2.A.29) family

  • Target Synonyms

    SLC25A11; SLC20A4; Mitochondrial 2-oxoglutarate/malate carrier protein; OGCP; Solute carrier family 25 member 11

  • Target Background

    The oxoglutarate/malate carrier transports 2-oxoglutarate across the inner membranes of mitochondria in an electroneutral exchange for malate or other dicarboxylic acids (summary by Iacobazzi et al., 1992 [PubMed 1457818]).

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