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The antibody against SLC6A1 was raised in rabbit using the Synthetic peptide from Human protein at AA range: Internal as the immunogen. This antibody exists as a non-conjugated antibody. The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. This antibody has been validated on WB, ELISA.
The antibody against SLC6A1 was raised in rabbit using the Synthetic peptide from Human protein at AA range: Internal as the immunogen. This antibody exists as a non-conjugated antibody. The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. This antibody has been validated on WB, ELISA.
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Western blot analysis of HELA MOUSE-BRAIN Cell Lysate using antibody. Secondary antibody was diluted at 1:20000
Immunohistochemical analysis of paraffin-embedded Human-brain, antibody was diluted at 1:1002
Immunohistochemical analysis of paraffin-embedded Rat-brain, antibody was diluted at 1:1003
| Cat.No | ADC-13054A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | SLC6A1 |
| Form | Liquid | Species Reactivity | Human, Mouse, Rat |
| Storage Buffer | PH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol., PBS | Purification Method | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Conjugate | Non-conjugated | Application | ELISA, WB |
| Storage | Upon receipt |
| Immunogen Description | Synthetic peptide from Human protein at AA range: Internal | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P30531 |
Uniprot Id
P30531
Target Species
Human
Target Name
SLC6A1
Target Full Name
Sodium- and chloride-dependent GABA transporter 1
Target Function
Terminates the action of GABA by its high affinity sodium-dependent reuptake into presynaptic terminals.
Target Involvement
Myoclonic-atonic epilepsy (MAE)
Target Subcellular Location
Cell membrane; Multi-pass membrane protein. Membrane; Multi-pass membrane protein. Cell junction, synapse, presynapse.
Target Protein Families
Sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family, SLC6A1 subfamily
Target Synonyms
GABATHG; GABATR; GABT 1; GABT1; GAT-1; GAT1; SC6A1_HUMAN; Slc6a1; Sodium and chloride dependent GABA transporter 1; Sodium- and chloride-dependent GABA transporter 1; Solute carrier family 6 (neurotransmitter transporter GABA) member 1; Solute carrier family 6 member 1
Target Background
The protein encoded by this gene is a gamma-aminobutyric acid (GABA) transporter that localizes to the plasma membrane. The encoded protein removes GABA from the synaptic cleft, restoring it to presynaptic terminals.
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