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The antibody against SLC6A12 was raised in rabbit using the Recombinant Human Sodium- and chloride-dependent betaine transporter protein (515-614AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
The antibody against SLC6A12 was raised in rabbit using the Recombinant Human Sodium- and chloride-dependent betaine transporter protein (515-614AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
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Immunohistochemistry of paraffin-embedded human liver tissue using SLC6A12 Antibody at dilution of 1:100
Immunohistochemistry of paraffin-embedded human kidney tissue using SLC6A12 Antibody at dilution of 1:1002
| Cat.No | ADC-16208A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | SLC6A12 |
| Target Synonyms | betaine/GABA), member 12 antibody; Solute carrier family 6 (neurotransmitter transporter, member 12 antibody; Solute carrier family 6 member 12 antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Antigen affinity purified |
| Conjugate | Non-conjugated | Application | ELISA, IHC |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Sodium- and chloride-dependent betaine transporter protein (515-614AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P48065 |
Uniprot Id
P48065
Target Species
Human
Target Name
SLC6A12
Target Full Name
Sodium- and chloride-dependent betaine transporter
Target Function
Transports betaine and GABA. May have a role in regulation of GABAergic transmission in the brain through the reuptake of GABA into presynaptic terminals, as well as in osmotic regulation.
Target Subcellular Location
Membrane; Multi-pass membrane protein.
Target Protein Families
Sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family, SLC6A12 subfamily
Target Tissue Specificity
Liver, heart, skeletal muscle, placenta, and a widespread distribution in the brain.
Target Synonyms
Betaine/GABA transporter 1; BGT-1; BGT1; Gamma aminobutyric acid transporter; GAT2; Na(+)/Cl(-) betaine/GABA transporter; S6A12_HUMAN; Slc6a12; Sodium- and chloride-dependent betaine transporter; Solute carrier family 6 (neurotransmitter transporter), member 12; Solute carrier family 6 (neurotransmitter transporter, betaine/GABA), member 12; Solute carrier family 6 member 12
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