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The antibody against SNUPN was raised in rabbit using the Human SNUPN as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC, IF.
The antibody against SNUPN was raised in rabbit using the Human SNUPN as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC, IF.
$600.00
| Cat.No | ADC-51788A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | SNUPN |
| Target Synonyms | 0610031A09Rik antibody; KPNBL antibody; MGC134006 antibody; MGC95000 antibody; RNA U transporter 1 antibody; RNA | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.02% sodium azide | Purification Method | Antigen affinity purified |
| Conjugate | Non-conjugated | Application | ELISA, IF, IHC, WB |
| Storage | Upon receipt |
| Immunogen Description | Human SNUPN | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | O95149 |
Uniprot Id
O95149
Target Species
Human
Target Name
SNUPN
Target Full Name
Snurportin-1
Target Function
Functions as an U snRNP-specific nuclear import adapter. Involved in the trimethylguanosine (m3G)-cap-dependent nuclear import of U snRNPs. Binds specifically to the terminal m3G-cap U snRNAs.
Target Subcellular Location
Nucleus. Cytoplasm.
Target Protein Families
Snurportin family
Target Synonyms
0610031A09Rik; KPNBL; MGC134006; MGC95000; RNA U transporter 1; RNA, U transporter 1; RNUT 1; RNUT1; SNUPN; Snupn1; Snurportin 1; Snurportin-1; Snurportin1; SPN1; SPN1_HUMAN; wu:fc41a03; zgc:77819
Target Background
The nuclear import of the spliceosomal snRNPs U1, U2, U4 and U5, is dependent on the presence of a complex nuclear localization signal. The latter is composed of the 5'-2, 2, 7-terminal trimethylguanosine (m3G) cap structure of the U snRNA and the Sm core domain. The protein encoded by this gene interacts specifically with m3G-cap and functions as an snRNP-specific nuclear import receptor. Alternatively spliced transcript variants encoding the same protein have been identified for this gene.
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