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The antibody against SNX14 was raised in rabbit using the Recombinant Human Sorting nexin-14 protein (601-893AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
The antibody against SNX14 was raised in rabbit using the Recombinant Human Sorting nexin-14 protein (601-893AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
$299.00
Immunohistochemistry of paraffin-embedded human liver tissue using SNX14 Antibody at dilution of 1:100
Immunohistochemistry of paraffin-embedded human adrenal gland tissue using SNX14 Antibody at dilution of 1:1002
Immunofluorescent analysis of HepG2 cells using SNX14 Antibody at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)3
| Cat.No | ADC-15247A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | SNX14 |
| Target Synonyms | MGC13217 antibody; RGS-PX2 antibody; RP11-321N4.2 antibody; Snx14 antibody; SNX14_HUMAN antibody; Sorting nexin 14 antibody; Sorting nexin-14 antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, IF, IHC |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Sorting nexin-14 protein (601-893AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9Y5W7 |
Uniprot Id
Q9Y5W7
Target Species
Human
Target Name
SNX14
Target Full Name
Sorting nexin-14
Target Function
Plays a role in maintaining normal neuronal excitability and synaptic transmission. May be involved in several stages of intracellular trafficking. Required for autophagosome clearance, possibly by mediating the fusion of lysosomes with autophagosomes. Binds phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2), a key component of late endosomes/lysosomes. Does not bind phosphatidylinositol 3-phosphate (PtdIns(3P)).
Target Involvement
Spinocerebellar ataxia, autosomal recessive, 20 (SCAR20)
Target Subcellular Location
Lysosome membrane; Multi-pass membrane protein. Late endosome membrane; Multi-pass membrane protein. Cell projection, dendrite.
Target Protein Families
Sorting nexin family
Target Tissue Specificity
Widely expressed both in fetal and adult tissues.
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