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The antibody against SOAT2 was raised in rabbit using the Recombinant Human Sterol O-acyltransferase 2 protein (1-120AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.
The antibody against SOAT2 was raised in rabbit using the Recombinant Human Sterol O-acyltransferase 2 protein (1-120AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.
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Immunohistochemistry of paraffin-embedded human liver tissue using SOAT2 Antibody at dilution of 1:1002
| Cat.No | ADC-16563A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | SOAT2 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. |
| Purification Method | Antigen affinity purified | Conjugate | Non-conjugated |
| Application | ELISA, IHC, WB | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Sterol O-acyltransferase 2 protein (1-120AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | O75908 |
Uniprot Id
O75908
Target Species
Human
Target Name
SOAT2
Target Full Name
Sterol O-acyltransferase 2
Target Function
Catalyzes the formation of fatty acid-cholesterol esters, which are less soluble in membranes than cholesterol. Plays a role in lipoprotein assembly and dietary cholesterol absorption. Utilizes oleoyl-CoA ((9Z)-octadecenoyl-CoA) and linolenoyl-CoA ((9Z,12Z,15Z)-octadecatrienoyl-CoA) as substrates. May provide cholesteryl esters for lipoprotein secretion from hepatocytes and intestinal mucosa.; Has lower enzymatic activity compared to isoform 1.; Has lower enzymatic activity compared to isoform 1.
Target Subcellular Location
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Target Protein Families
Membrane-bound acyltransferase family, Sterol o-acyltransferase subfamily
Target Tissue Specificity
Expression seems confined in hepatocytes and enterocytes.
Target Synonyms
SOAT2; ACACT2; ACAT2; Sterol O-acyltransferase 2; EC 2.3.1.26; Acyl-coenzyme A:cholesterol acyltransferase 2; ACAT-2; Cholesterol acyltransferase 2
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