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The antibody against SOD2 was raised in rabbit using the Synthesized peptide derived from the Internal region of Human SOD-2. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, ELISA.
The antibody against SOD2 was raised in rabbit using the Synthesized peptide derived from the Internal region of Human SOD-2. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, ELISA.
$167.00
Western Blot analysis of NIH-3T3 cells using SOD-2 Polyclonal Antibody
| Cat.No | ADC-36802A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | SOD2 |
| Target Synonyms | mitochondrial antibody; Superoxide dismutase 2 mitochondrial antibody | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 0.5% BSA and 0.02% sodium azide., Liquid in PBS containing 50% glycerol | Purification Method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Conjugate | Non-conjugated | Application | ELISA, WB |
| Storage | Upon receipt |
| Immunogen Description | Synthesized peptide derived from the Internal region of Human SOD-2. | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P04179 |
Uniprot Id
P04179
Target Species
Human
Target Name
SOD2
Target Full Name
Superoxide dismutase [Mn], mitochondrial
Target Function
Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.
Target Involvement
Microvascular complications of diabetes 6 (MVCD6)
Target Subcellular Location
Mitochondrion matrix.
Target Protein Families
Iron/manganese superoxide dismutase family
Target Synonyms
Indophenoloxidase B; IPO B; IPOB; Manganese containing superoxide dismutase; Manganese SOD; Manganese superoxide dismutase; Mangano superoxide dismutase; Mn SOD; Mn superoxide dismutase; MNSOD; MVCD6; SOD 2; SOD2; SODM_HUMAN; Superoxide dismutase [Mn] mitochondrial; Superoxide dismutase [Mn], mitochondrial; Superoxide dismutase 2 mitochondrial
Target Background
This gene is a member of the iron/manganese superoxide dismutase family. It encodes a mitochondrial protein that forms a homotetramer and binds one manganese ion per subunit. This protein binds to the superoxide byproducts of oxidative phosphorylation and converts them to hydrogen peroxide and diatomic oxygen. Mutations in this gene have been associated with idiopathic cardiomyopathy (IDC), premature aging, sporadic motor neuron disease, and cancer. Alternative splicing of this gene results in multiple transcript variants. A related pseudogene has been identified on chromosome 1.
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