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The antibody against SRCIN1 was raised in rabbit using the Synthesized peptide derived from the Internal region of Human p140Cap. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, ELISA.
The antibody against SRCIN1 was raised in rabbit using the Synthesized peptide derived from the Internal region of Human p140Cap. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, ELISA.
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Western Blot analysis of HepG2 cells using p140Cap Polyclonal Antibody
Western Blot analysis of 293T HELA cells using p140Cap Polyclonal Antibody2
| Cat.No | ADC-37948A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | SRCIN1 |
| Form | Liquid | Species Reactivity | Human, Mouse, Rat |
| Isotype | IgG | Storage Buffer | 0.5% BSA and 0.02% sodium azide., Liquid in PBS containing 50% glycerol |
| Purification Method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | Conjugate | Non-conjugated |
| Application | ELISA, WB | Storage | Upon receipt |
| Immunogen Description | Synthesized peptide derived from the Internal region of Human p140Cap. | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9C0H9 |
Uniprot Id
Q9C0H9
Target Species
Human
Target Name
SRCIN1
Target Full Name
SRC kinase signaling inhibitor 1
Target Function
Acts as a negative regulator of SRC by activating CSK which inhibits SRC activity and downstream signaling, leading to impaired cell spreading and migration. Regulates dendritic spine morphology. Involved in calcium-dependent exocytosis. May play a role in neurotransmitter release or synapse maintenance.
Target Subcellular Location
Cytoplasm. Cytoplasm, cytoskeleton. Cell projection, axon. Cell projection, dendrite. Cell junction, synapse, presynapse. Cell junction, synapse, postsynapse. Cell junction, synapse, postsynaptic density.
Target Protein Families
SRCIN1 family
Target Tissue Specificity
Expressed in some primary breast carcinomas where its presence is significantly associated with increased tumor size. Not detected in normal breast tissue.
Target Synonyms
p130Cas associated protein; p130Cas-associated protein; P140; p140Cap; SNAP-25-interacting protein; SNIP; SRC kinase signaling inhibitor 1; SRCIN1; SRCN1_HUMAN
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