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The antibody against SRM was raised in rabbit using the Recombinant Human Spermidine synthase protein (17-302AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC.
The antibody against SRM was raised in rabbit using the Recombinant Human Spermidine synthase protein (17-302AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC.
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Immunohistochemistry of paraffin-embedded human colon cancer using SRM Antibody at dilution of 1:1002
| Cat.No | ADC-50468A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | SRM |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IHC, WB | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Spermidine synthase protein (17-302AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P19623 |
Uniprot Id
P19623
Target Species
Human
Target Name
SRM
Target Full Name
Spermidine synthase
Target Function
Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM). Has a strong preference for putrescine as substrate, and has very low activity towards 1,3-diaminopropane. Has extremely low activity towards spermidine.
Target Protein Families
Spermidine/spermine synthase family
Target Research Area
Metabolism
Target Synonyms
OTTHUMP00000002170; PAPT; Putrescine aminopropyltransferase; SPDSY; SPEE_HUMAN; Spermidine synthase 1; Spermidine synthase; SPS1; Srm; SRML1
Target Background
The polyamines putrescine, spermine, and spermidine are ubiquitous polycationic mediators of cell growth and differentiation. Spermidine synthase is one of four enzymes in the polyamine-biosynthetic pathway and carries out the final step of spermidine biosynthesis. This enzyme catalyzes the conversion of putrescine to spermidine using decarboxylated S-adenosylmethionine as the cofactor.
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