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Rabbit anti-Human SRPR Polyclonal Antibody

The antibody against SRPR was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human SRPR (NP_003130.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-03619A

The antibody against SRPR was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human SRPR (NP_003130.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

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Specifications


Cat.No ADA-03619A ClonalityPolyclonal
Host SpeciesRabbitTarget NameSRPR
Target SynonymsDP; SRPR; SralphaFormLiquid
Species ReactivityHumanIsotypeIgG
Storage Buffer50% Glycerol, PBS with 0.02% sodium azide, pH7.3.Purification MethodAffinity purification
Positive SamplesA-549, HT-1080ApplicationELISA, WB

Immunogen Information


Immunogen DescriptionRecombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human SRPR (NP_003130.2).Target SpeciesHuman
Uniprot IDP08240Immunogen Sequence
Background Information
  • Uniprot Id

    P08240

  • Target Species

    Human

  • Target Name

    SRPRA

  • Target Full Name

    Signal recognition particle receptor subunit alpha

  • Target Function

    Component of the SRP (signal recognition particle) receptor. Ensures, in conjunction with the signal recognition particle, the correct targeting of the nascent secretory proteins to the endoplasmic reticulum membrane system.

  • Target Subcellular Location

    Endoplasmic reticulum membrane; Peripheral membrane protein. Note=Thought to be anchored in the membrane through an interaction with SR-beta, which contains a bona fide transmembrane domain.

  • Target Protein Families

    GTP-binding SRP family

  • Target Synonyms

    Docking protein alpha; DP alpha; DP; DP-alpha; DPalpha; MGC17355; MGC3650; MGC9571; signal recognition particle receptor (docking protein); Signal recognition particle receptor alpha subunit; Signal recognition particle receptor; Signal recognition particle receptor subunit alpha; SR alpha; SR-alpha; SRalpha; SRP alpha; SRPalpha; SRPR; SRPR_HUMAN

  • Target Background

    The gene encodes a subunit of the endoplasmic reticulum signal recognition particle receptor that, in conjunction with the signal recognition particle, is involved in the targeting and translocation of signal sequence tagged secretory and membrane proteins across the endoplasmic reticulum. Alternative splicing results in multiple transcript variants.

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