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The antibody against SRPR was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human SRPR (NP_003130.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against SRPR was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human SRPR (NP_003130.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-03619A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | SRPR |
| Target Synonyms | DP; SRPR; Sralpha | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | A-549, HT-1080 | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human SRPR (NP_003130.2). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | P08240 | Immunogen Sequence |
Uniprot Id
P08240
Target Species
Human
Target Name
SRPRA
Target Full Name
Signal recognition particle receptor subunit alpha
Target Function
Component of the SRP (signal recognition particle) receptor. Ensures, in conjunction with the signal recognition particle, the correct targeting of the nascent secretory proteins to the endoplasmic reticulum membrane system.
Target Subcellular Location
Endoplasmic reticulum membrane; Peripheral membrane protein. Note=Thought to be anchored in the membrane through an interaction with SR-beta, which contains a bona fide transmembrane domain.
Target Protein Families
GTP-binding SRP family
Target Synonyms
Docking protein alpha; DP alpha; DP; DP-alpha; DPalpha; MGC17355; MGC3650; MGC9571; signal recognition particle receptor (docking protein); Signal recognition particle receptor alpha subunit; Signal recognition particle receptor; Signal recognition particle receptor subunit alpha; SR alpha; SR-alpha; SRalpha; SRP alpha; SRPalpha; SRPR; SRPR_HUMAN
Target Background
The gene encodes a subunit of the endoplasmic reticulum signal recognition particle receptor that, in conjunction with the signal recognition particle, is involved in the targeting and translocation of signal sequence tagged secretory and membrane proteins across the endoplasmic reticulum. Alternative splicing results in multiple transcript variants.
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