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The antibody against SRR was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-340 of human SRR (NP_068766.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against SRR was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-340 of human SRR (NP_068766.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-01002A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | SRR |
| Target Synonyms | ILV1; ISO1; SRR | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Rat brain, Mouse brain, SH-SY5Y, U-87MG | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1-340 of human SRR (NP_068766.1). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q9GZT4 | Immunogen Sequence |
Uniprot Id
Q9GZT4
Target Species
Human
Target Name
SRR
Target Full Name
Serine racemase
Target Function
Catalyzes the synthesis of D-serine from L-serine. D-serine is a key coagonist with glutamate at NMDA receptors. Has dehydratase activity towards both L-serine and D-serine.
Target Protein Families
Serine/threonine dehydratase family
Target Tissue Specificity
Brain: expressed at high levels in hippocampus and corpus callosum, intermediate levels in substantia nigra and caudate, and low levels in amygdala, thalamus, and subthalamic nuclei. Expressed in heart, skeletal muscle, kidney and liver.
Target Research Area
Neuroscience
Target Synonyms
D serine ammonia lyase; D serine dehydratase; D-serine ammonia-lyase; D-serine dehydratase; ILV1; ISO1; L serine ammonia lyase; L serine dehydratase; L-serine ammonia-lyase; L-serine dehydratase; Serine racemase; srr; SRR_HUMAN
Target Background
Enables several functions, including L-serine ammonia-lyase activity; PDZ domain binding activity; and anion binding activity. Involved in pyruvate biosynthetic process; response to lipopolysaccharide; and serine family amino acid metabolic process. Located in cytoplasm and neuronal cell body.
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