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The antibody against SSX1 was raised in rabbit using the Recombinant Human Protein SSX1 protein (112-188AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
The antibody against SSX1 was raised in rabbit using the Recombinant Human Protein SSX1 protein (112-188AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
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Immunohistochemistry of paraffin-embedded human testis tissue using SSX1 Antibody at dilution of 1:100
Immunofluorescent analysis of PC-3 cells using SSX1 Antibody at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)2
| Cat.No | ADC-11994A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | SSX1 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IF, IHC | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Protein SSX1 protein (112-188AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q16384 |
Uniprot Id
Q16384
Target Species
Human
Target Name
SSX1
Target Full Name
Protein SSX1
Target Function
Could act as a modulator of transcription.
Target Involvement
A chromosomal aberration involving SSX1 may be a cause of synovial sarcoma. Translocation t(X;18)(p11.2;q11.2). The translocation is specifically found in more than 80% of synovial sarcoma. The fusion products SSXT-SSX1 or SSXT-SSX2 are probably responsible for transforming activity. Heterogeneity in the position of the breakpoint can occur (low frequency).
Target Protein Families
SSX family
Target Tissue Specificity
Expressed at high level in the testis. Expressed at low level in thyroid. Not detected in tonsil, colon, lung, spleen, prostate, kidney, striated and smooth muscles. Detected in rhabdomyosarcoma and fibrosarcoma cell lines. Not detected in mesenchymal and
Target Research Area
Epigenetics and Nuclear Signaling
Target Synonyms
Cancer/testis antigen 5.1; Cancer/testis antigen family 5 member 1; CT5.1; MGC150425; MGC5162; Protein SSX1; sarcoma; synovial; X chromosome related 1; SSRC; SSX1; SSX1_HUMAN; Synovial sarcoma; Synovial sarcoma; X breakpoint 1 ; X breakpoint 1
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