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The antibody against STX12 was raised in rabbit using the Recombinant Human Syntaxin-12 protein (1-250AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
The antibody against STX12 was raised in rabbit using the Recombinant Human Syntaxin-12 protein (1-250AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
$299.00
Immunohistochemistry of paraffin-embedded human lung cancer using STX12 Antibody at dilution of 1:100
Immunohistochemistry of paraffin-embedded human placenta tissue using STX12 Antibody at dilution of 1:1002
Immunohistochemistry of paraffin-embedded human pancreatic tissue using STX12 Antibody at dilution of 1:1003
| Cat.No | ADC-40499A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | STX12 |
| Target Synonyms | MGC51957 antibody; Stx12 antibody; STX12_HUMAN antibody; STX13 antibody; STX14 antibody; Syntaxin-12 antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Antigen affinity purified |
| Conjugate | Non-conjugated | Application | ELISA, IHC |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Syntaxin-12 protein (1-250AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q86Y82 |
Uniprot Id
Q86Y82
Target Species
Human
Target Name
STX12
Target Full Name
Syntaxin-12
Target Function
SNARE that acts to regulate protein transport between late endosomes and the trans-Golgi network. The SNARE complex containing STX6, STX12, VAMP4 and VTI1A mediates vesicle fusion (in vitro). Through complex formation with GRIP1, GRIA2 and NSG1 controls the intracellular fate of AMPAR and the endosomal sorting of the GRIA2 subunit toward recycling and membrane targeting.
Target Subcellular Location
Endosome membrane; Single-pass type IV membrane protein. Golgi apparatus membrane; Single-pass type IV membrane protein. Endomembrane system; Single-pass type IV membrane protein; Cytoplasmic side. Early endosome membrane; Single-pass type IV membrane protein. Recycling endosome membrane; Single-pass type IV membrane protein.
Target Protein Families
Syntaxin family
Target Synonyms
MGC51957; Stx12; STX12_HUMAN; STX13; STX14; Syntaxin-12
Target Background
Predicted to enable SNAP receptor activity and SNARE binding activity. Involved in autophagosome assembly; cholesterol efflux; and protein stabilization. Located in several cellular components, including membrane raft; phagocytic vesicle; and phagophore assembly site. Part of SNARE complex. Colocalizes with BLOC-1 complex.
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