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Rabbit anti-Human SUPT20H Polyclonal Antibody

The antibody against SUPT20H was raised in rabbit using the Synthetic peptide from AA range: 231-280 as the immunogen. This antibody exists as a non-conjugated antibody. The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. This antibody has been validated on WB, ELISA.

ADC-12908A

The antibody against SUPT20H was raised in rabbit using the Synthetic peptide from AA range: 231-280 as the immunogen. This antibody exists as a non-conjugated antibody. The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. This antibody has been validated on WB, ELISA.

$167.00

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Specifications


Cat.No ADC-12908A ClonalityPolyclonal
Host SpeciesRabbitTarget NameSUPT20H
FormLiquidSpecies ReactivityHuman, Mouse, Rat
Storage BufferPH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol., PBSPurification MethodThe antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
ConjugateNon-conjugatedApplicationELISA, WB
StorageUpon receipt

Immunogen Information


Immunogen DescriptionSynthetic peptide from AA range: 231-280Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ8NEM7
Background Information
  • Uniprot Id

    Q8NEM7

  • Target Species

    Human

  • Target Name

    SUPT20H

  • Target Full Name

    Transcription factor SPT20 homolog

  • Target Function

    Required for MAP kinase p38 (MAPK11, MAPK12, MAPK13 and/or MAPK14) activation during gastrulation. Required for down-regulation of E-cadherin during gastrulation by regulating E-cadherin protein level downstream from NCK-interacting kinase (NIK) and independently of the regulation of transcription by FGF signaling and Snail. Required for starvation-induced ATG9A trafficking during autophagy.

  • Target Subcellular Location

    Nucleus.

  • Target Protein Families

    SPT20 family

  • Target Tissue Specificity

    Highly expressed in testis, moderately in brain and pituitary gland. Expressed in several fetal tissues, including lung, brain, thymus and kidney. Expression is down-regulated in malignant prostate tissues.

  • Target Synonyms

    AA667204; AI450544; bA421P11.4; C13; C13orf19; D3Ertd300e; FA48A_HUMAN; FAM48A; FP757; p38-interacting protein; p38IP; Protein FAM48A; RGD1307812; SPT20

  • Target Background

    Predicted to enable transcription coregulator activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to act upstream of or within positive regulation of gluconeogenesis and positive regulation of transcription by RNA polymerase II. Part of SAGA-type complex.

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