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The antibody against SUPT20H was raised in rabbit using the Recombinant Human Transcription factor SPT20 homolog protein (580-779AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.
The antibody against SUPT20H was raised in rabbit using the Recombinant Human Transcription factor SPT20 homolog protein (580-779AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.
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Immunohistochemistry of paraffin-embedded human colon tissue using SUPT20H Antibody at dilution of 1:1002
| Cat.No | ADC-17153A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | SUPT20H |
| Form | Liquid | Species Reactivity | Human, Mouse |
| Isotype | IgG | Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. |
| Purification Method | Antigen affinity purified | Conjugate | Non-conjugated |
| Application | ELISA, IHC, WB | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Transcription factor SPT20 homolog protein (580-779AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q8NEM7 |
Uniprot Id
Q8NEM7
Target Species
Human
Target Name
SUPT20H
Target Full Name
Transcription factor SPT20 homolog
Target Function
Required for MAP kinase p38 (MAPK11, MAPK12, MAPK13 and/or MAPK14) activation during gastrulation. Required for down-regulation of E-cadherin during gastrulation by regulating E-cadherin protein level downstream from NCK-interacting kinase (NIK) and independently of the regulation of transcription by FGF signaling and Snail. Required for starvation-induced ATG9A trafficking during autophagy.
Target Subcellular Location
Nucleus.
Target Protein Families
SPT20 family
Target Tissue Specificity
Highly expressed in testis, moderately in brain and pituitary gland. Expressed in several fetal tissues, including lung, brain, thymus and kidney. Expression is down-regulated in malignant prostate tissues.
Target Synonyms
AA667204; AI450544; bA421P11.4; C13; C13orf19; D3Ertd300e; FA48A_HUMAN; FAM48A; FP757; p38-interacting protein; p38IP; Protein FAM48A; RGD1307812; SPT20
Target Background
Predicted to enable transcription coregulator activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to act upstream of or within positive regulation of gluconeogenesis and positive regulation of transcription by RNA polymerase II. Part of SAGA-type complex.
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