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The antibody against SYCP2 was raised in rabbit using the Synthesized peptide derived from the Internal region of Human SCP-2. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, ELISA.
The antibody against SYCP2 was raised in rabbit using the Synthesized peptide derived from the Internal region of Human SCP-2. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, ELISA.
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Western Blot analysis of SKOV3 BT474 Jurkat PC-3 U937 MCF7 cells using SCP-2 Polyclonal Antibody
| Cat.No | ADC-37232A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | SYCP2 |
| Target Synonyms | SYCP2 antibody; SCP2 antibody; Synaptonemal complex protein 2 antibody; SCP-2 antibody; Synaptonemal complex lateral element protein antibody; hsSCP2 antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.5% BSA and 0.02% sodium azide., Liquid in PBS containing 50% glycerol | Purification Method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Conjugate | Non-conjugated | Application | ELISA, WB |
| Storage | Upon receipt |
| Immunogen Description | Synthesized peptide derived from the Internal region of Human SCP-2. | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9BX26 |
Uniprot Id
Q9BX26
Target Species
Human
Target Name
SYCP2
Target Full Name
Synaptonemal complex protein 2
Target Function
Major component of the axial/lateral elements of synaptonemal complexes (SCS) during meiotic prophase. Plays a role in the assembly of synaptonemal complexes. Required for normal meiotic chromosome synapsis during oocyte and spermatocyte development and for normal male and female fertility. Required for insertion of SYCP3 into synaptonemal complexes. May be involved in the organization of chromatin by temporarily binding to DNA scaffold attachment regions. Requires SYCP3, but not SYCP1, in order to be incorporated into the axial/lateral elements.
Target Subcellular Location
Nucleus. Chromosome.
Target Protein Families
SYCP2 family
Target Synonyms
SYCP2; SCP2; Synaptonemal complex protein 2; SCP-2; Synaptonemal complex lateral element protein; hsSCP2
Target Background
The synaptonemal complex is a proteinaceous structure that links homologous chromosomes during the prophase of meiosis. The protein encoded by this gene is a major component of the synaptonemal complex and may bind DNA at scaffold attachment regions. The encoded protein requires synaptonemal complex protein 3, but not 1, for inclusion in the synaptonemal complex.
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