Rabbit anti-Human TAC1 Polyclonal Antibody

Uniprot Id

P20366

Target Species

Human

Target Name

TAC1

Target Full Name

Protachykinin-1

Target Function

Tachykinins are active peptides which excite neurons, evoke behavioral responses, are potent vasodilators and secretagogues, and contract (directly or indirectly) many smooth muscles.

Target Subcellular Location

Secreted.

Target Protein Families

Tachykinin family

Target Research Area

Neuroscience

Target Synonyms

C-terminal-flanking peptide; Hs.2563; neurokinin 1; neurokinin 2; neurokinin A; neurokinin alpha; Neuromedin L; neuropeptide gamma; neuropeptide K; NK2; NKA; NKNA; NPK; PPT; preprotachykinin; protachykinin; protachykinin-1; Substance K; SubstanceP; TAC1; TAC2; TAC2; formerly; Tachykinin 1; tachykinin 2; tachykinin 2; formerly; Tachykinin precursor 1; tachykinin; precursor 1 (substance K; substance P; neurokinin 1; neurokinin 2; neuromedin L; neurokinin alpha; neuropeptide K; neuropeptide gamma); Tachykinin1; TKN1_HUMAN

Target Background

This gene encodes four products of the tachykinin peptide hormone family, substance P and neurokinin A, as well as the related peptides, neuropeptide K and neuropeptide gamma. These hormones are thought to function as neurotransmitters which interact with nerve receptors and smooth muscle cells. They are known to induce behavioral responses and function as vasodilators and secretagogues. Substance P is an antimicrobial peptide with antibacterial and antifungal properties. Multiple transcript variants encoding different isoforms have been found for this gene.