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The antibody against TARS2 was raised in rabbit using the Recombinant Human Threonine--tRNA ligase, mitochondrial protein (369-718AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
The antibody against TARS2 was raised in rabbit using the Recombinant Human Threonine–tRNA ligase, mitochondrial protein (369-718AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
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Immunohistochemistry of paraffin-embedded human kidney tissue using TARS2 Antibody at dilution of 1:100
Immunohistochemistry of paraffin-embedded human small intestine tissue using TARS2 Antibody at dilution of 1:1002
| Cat.No | ADC-23359A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | TARS2 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IHC | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Threonine--tRNA ligase, mitochondrial protein (369-718AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9BW92 |
Uniprot Id
Q9BW92
Target Species
Human
Target Name
TARS2
Target Full Name
Threonine--tRNA ligase, mitochondrial
Target Function
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged tRNA(Thr) via its editing domain.
Target Involvement
Combined oxidative phosphorylation deficiency 21 (COXPD21)
Target Subcellular Location
Mitochondrion matrix.
Target Protein Families
Class-II aminoacyl-tRNA synthetase family
Target Research Area
Epigenetics and Nuclear Signaling
Target Synonyms
TARS2; TARSL1; Threonine--tRNA ligase; mitochondrial; EC 6.1.1.3; Threonyl-tRNA synthetase; ThrRS; Threonyl-tRNA synthetase-like 1
Target Background
This gene encodes a member of the class-II aminoacyl-tRNA synthetase family. The encoded protein is a mitochondrial aminoacyl-tRNA synthetase. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 4.
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