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Rabbit anti-Human TFF2 Polyclonal Antibody

The antibody against TFF2 was raised in rabbit using the Recombinant Human Trefoil factor 2 protein (24-129AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.

ADC-40196A

The antibody against TFF2 was raised in rabbit using the Recombinant Human Trefoil factor 2 protein (24-129AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.

$299.00

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Specifications


Cat.No ADC-40196A ClonalityPolyclonal
Host SpeciesRabbitTarget NameTFF2
FormLiquidSpecies ReactivityHuman
IsotypeIgGStorage Buffer50% Glycerol, PBS with 0.02% sodium azide, pH7.3.
Purification MethodAntigen affinity purifiedConjugateNon-conjugated
ApplicationELISA, IHCStorageUpon receipt

Immunogen Information


Immunogen DescriptionRecombinant Human Trefoil factor 2 protein (24-129AA)Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ03403
Background Information
  • Uniprot Id

    Q03403

  • Target Species

    Human

  • Target Name

    TFF2

  • Target Full Name

    Trefoil factor 2

  • Target Function

    Inhibits gastrointestinal motility and gastric acid secretion. Could function as a structural component of gastric mucus, possibly by stabilizing glycoproteins in the mucus gel through interactions with carbohydrate side chains.

  • Target Subcellular Location

    Secreted.

  • Target Tissue Specificity

    Stomach.

  • Target Synonyms

    SP; SML1; TFF2

  • Target Background

    Members of the trefoil family are characterized by having at least one copy of the trefoil motif, a 40-amino acid domain that contains three conserved disulfides. They are stable secretory proteins expressed in gastrointestinal mucosa. Their functions are not defined, but they may protect the mucosa from insults, stabilize the mucus layer and affect healing of the epithelium. The encoded protein inhibits gastric acid secretion. This gene and two other related trefoil family member genes are found in a cluster on chromosome 21.

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