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The antibody against THAP12 was raised in rabbit using the Recombinant Human 52 kDa repressor of the inhibitor of the protein kinase protein (612-761AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC.
The antibody against THAP12 was raised in rabbit using the Recombinant Human 52 kDa repressor of the inhibitor of the protein kinase protein (612-761AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC.
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Immunohistochemistry of paraffin-embedded human lung tissue using THAP12 Antibody at dilution of 1:1002
| Cat.No | ADC-49574A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | THAP12 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IHC, WB | Storage | Upon receipt |
| Immunogen Description | Recombinant Human 52 kDa repressor of the inhibitor of the protein kinase protein (612-761AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | O43422 |
Uniprot Id
O43422
Target Species
Human
Target Name
THAP12
Target Full Name
52 kDa repressor of the inhibitor of the protein kinase
Target Function
Upstream regulator of interferon-induced serine/threonine protein kinase R (PKR). May block the PKR-inhibitory function of DNAJC3, resulting in restoration of kinase activity and suppression of cell growth.
Target Research Area
Signal Transduction
Target Synonyms
THAP12; DAP4; P52RIPK; PRKRIR; THAP0; 52 kDa repressor of the inhibitor of the protein kinase; p52rIPK; 58 kDa interferon-induced protein kinase-interacting protein; p58IPK-interacting protein; Death-associated protein 4; THAP domain-containing protein 0; THAP domain-containing protein 12
Target Background
Predicted to enable DNA binding activity; metal ion binding activity; and protein dimerization activity. Predicted to be involved in negative regulation of cell population proliferation and signal transduction. Predicted to be located in nucleus.
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