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Rabbit anti-Human THAP4 Polyclonal Antibody

The antibody against THAP4 was raised in rabbit using the Synthesized peptide derived from the Internal region of Human THAP4. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, IHC, ELISA.

ADC-37469A

The antibody against THAP4 was raised in rabbit using the Synthesized peptide derived from the Internal region of Human THAP4. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, IHC, ELISA.

$167.00

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Specifications


Cat.No ADC-37469A ClonalityPolyclonal
Host SpeciesRabbitTarget NameTHAP4
Target SynonymsTHAP4 antibody; CGI-36 antibody; PP238 antibody; THAP domain-containing protein 4 antibodyFormLiquid
Species ReactivityHuman, Mouse, Rat, MonkeyIsotypeIgG
Storage Buffer0.5% BSA and 0.02% sodium azide., Liquid in PBS containing 50% glycerolPurification MethodThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ConjugateNon-conjugatedApplicationELISA, IHC, WB
StorageUpon receipt

Immunogen Information


Immunogen DescriptionSynthesized peptide derived from the Internal region of Human THAP4.Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ8WY91
Background Information
  • Uniprot Id

    Q8WY91

  • Target Species

    Human

  • Target Name

    THAP4

  • Target Full Name

    Peroxynitrite isomerase THAP4

  • Target Function

    Heme-binding protein able to scavenge peroxynitrite and to protect free L-tyrosine against peroxynitrite-mediated nitration, by acting as a peroxynitrite isomerase that converts peroxynitrite to nitrate. Therefore, this protein likely plays a role in peroxynitrite sensing and in the detoxification of reactive nitrogen and oxygen species (RNS and ROS, respectively). Is able to bind nitric oxide (NO) in vitro, but may act as a sensor of peroxynitrite levels in vivo, possibly modulating the transcriptional activity residing in the N-terminal region.

  • Target Subcellular Location

    Cytoplasm. Nucleus.

  • Target Synonyms

    THAP4; CGI-36; PP238; THAP domain-containing protein 4

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