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Rabbit anti-Human THEMIS Polyclonal Antibody

The antibody against THEMIS was raised in rabbit using the Recombinant Human Protein THEMIS protein (547-641AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC, IF.

ADC-06412A

The antibody against THEMIS was raised in rabbit using the Recombinant Human Protein THEMIS protein (547-641AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC, IF.

$299.00

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Specifications


Cat.No ADC-06412A ClonalityPolyclonal
Host SpeciesRabbitTarget NameTHEMIS
FormLiquidSpecies ReactivityHuman
IsotypeIgGStorage Buffer0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4
Purification Method>95%, Protein G purifiedConjugateNon-conjugated
ApplicationELISA, IF, IHC, WBStorageUpon receipt

Immunogen Information


Immunogen DescriptionRecombinant Human Protein THEMIS protein (547-641AA)Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ8N1K5
Background Information
  • Uniprot Id

    Q8N1K5

  • Target Species

    Human

  • Target Name

    THEMIS

  • Target Full Name

    Protein THEMIS

  • Target Function

    Plays a central role in late thymocyte development by controlling both positive and negative T-cell selection. Required to sustain and/or integrate signals required for proper lineage commitment and maturation of T-cells. Regulates T-cell development through T-cell antigen receptor (TCR) signaling and in particular through the regulation of calcium influx and phosphorylation of Erk.

  • Target Subcellular Location

    Cytoplasm. Nucleus.

  • Target Protein Families

    Themis family

  • Target Synonyms

    C6orf190; C6orf207; MGC163388; Protein THEMIS; SIGNALING PHOSPHOPROTEIN SPECIFIC FOR T CELLS; SPOT; THEMIS; THMS1_HUMAN; Thymocyte expressed molecule involved in selection; Thymocyte selection associated; Thymocyte selection pathway associated; Thymocyte-expressed molecule involved in selection; TSEPA

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