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The antibody against TM6SF2 was raised in rabbit using the Recombinant Human Transmembrane 6 superfamily member 2 protein (290-331AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
The antibody against TM6SF2 was raised in rabbit using the Recombinant Human Transmembrane 6 superfamily member 2 protein (290-331AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
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Immunohistochemistry of paraffin-embedded human liver tissue using TM6SF2 Antibody at dilution of 1:100
Immunohistochemistry of paraffin-embedded human brain tissue using TM6SF2 Antibody at dilution of 1:1002
| Cat.No | ADC-09109A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | TM6SF2 |
| Target Synonyms | TM6S2_HUMAN antibody; Tm6sf2 antibody; Transmembrane 6 superfamily member 2 antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, IF, IHC |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Transmembrane 6 superfamily member 2 protein (290-331AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9BZW4 |
Uniprot Id
Q9BZW4
Target Species
Human
Target Name
TM6SF2
Target Full Name
Transmembrane 6 superfamily member 2
Target Function
Regulator of liver fat metabolism influencing triglyceride secretion and hepatic lipid droplet content. May function as sterol isomerase.
Target Subcellular Location
Endoplasmic reticulum membrane; Multi-pass membrane protein. Endoplasmic reticulum-Golgi intermediate compartment membrane; Multi-pass membrane protein.
Target Protein Families
TM6SF family
Target Tissue Specificity
Substantial expression in liver and intestine, whereas all other tissues analyzed show low levels.
Target Synonyms
TM6S2_HUMAN; Tm6sf2; Transmembrane 6 superfamily member 2
Target Background
Enables identical protein binding activity. Involved in regulation of lipid metabolic process. Located in endoplasmic reticulum membrane and endoplasmic reticulum-Golgi intermediate compartment membrane.
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