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The antibody against TMEM25 was raised in rabbit using the Recombinant Human Transmembrane protein 25 protein (27-322AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.
The antibody against TMEM25 was raised in rabbit using the Recombinant Human Transmembrane protein 25 protein (27-322AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.
$299.00
| Cat.No | ADC-50103A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | TMEM25 |
| Target Synonyms | 0610039J01Rik antibody; FLJ14399 antibody; Tmem25 antibody; TMM25_HUMAN antibody; Transmembrane protein 25 antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Transmembrane protein 25 protein (27-322AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q86YD3 |
Uniprot Id
Q86YD3
Target Species
Human
Target Name
TMEM25
Target Full Name
Transmembrane protein 25
Target Function
In neurons, modulates the degradation of NMDA receptor GRIN2B subunit. Plays a role in the regulation of neuronal excitability.
Target Subcellular Location
[Isoform 1]: Cell membrane; Single-pass type I membrane protein.; [Isoform 4]: Cell membrane; Single-pass type I membrane protein.; [Isoform 2]: Secreted.; [Isoform 3]: Secreted.; Late endosome. Lysosome.
Target Tissue Specificity
Expressed throughout the brain with higher levels in the pyramidal cell layer of the hippocampal CA1 and CA3 regions. Also highly expressed iwhith the hippocampal dentate gyrus region and cerebellum and in scattered neurons in the cerebral cortex.
Target Research Area
Cell Biology
Target Synonyms
0610039J01Rik; FLJ14399; Tmem25; TMM25_HUMAN; Transmembrane protein 25
Target Background
Predicted to be involved in negative regulation of excitatory postsynaptic potential and regulation of protein stability. Predicted to be located in late endosome and lysosome.
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