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The antibody against TMEM33 was raised in rabbit using the Recombinant Human Transmembrane protein 33 protein (177-247AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
The antibody against TMEM33 was raised in rabbit using the Recombinant Human Transmembrane protein 33 protein (177-247AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
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Immunohistochemistry of paraffin-embedded human adrenal gland tissue using TMEM33 Antibody at dilution of 1:100
Immunofluorescent analysis of Hela cells using TMEM33 Antibody at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)2
| Cat.No | ADC-22364A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | TMEM33 |
| Target Synonyms | TMEM33; DB83; Transmembrane protein 33; Protein DB83; SHINC-3 | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, IF, IHC |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Transmembrane protein 33 protein (177-247AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P57088 |
Uniprot Id
P57088
Target Species
Human
Target Name
TMEM33
Target Full Name
Transmembrane protein 33
Target Function
Acts as a regulator of the tubular endoplasmic reticulum (ER) network. Suppresses the RTN3/4-induced formation of the ER tubules. Positively regulates PERK-mediated and IRE1-mediated unfolded protein response signaling.
Target Subcellular Location
Endoplasmic reticulum membrane; Multi-pass membrane protein. Melanosome. Nucleus envelope.
Target Protein Families
PER33/POM33 family
Target Tissue Specificity
Prostate cancer and several cancer cell lines (at protein level). Widely expressed. Expressed at higher levels in endocrine-resistant breast cancer cells as compared to endocrine-sensitive breast cancer cells. Expressed at higher levels in early recurrenc
Target Synonyms
TMEM33; DB83; Transmembrane protein 33; Protein DB83; SHINC-3
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