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The antibody against TMEM47 was raised in rabbit using the Recombinant Human Transmembrane protein 47 protein (42-82AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
The antibody against TMEM47 was raised in rabbit using the Recombinant Human Transmembrane protein 47 protein (42-82AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
$299.00
Immunofluorescent analysis of U251 cells using TMEM47 Antibody at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
Immunohistochemistry analysis of human brain tissue using TMEM47 Antibody at dilution of 1:1002
Immunofluorescent analysis of Hela cells using TMEM47 Antibody at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)3
| Cat.No | ADC-21245A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | TMEM47 |
| Target Synonyms | TMEM47; BCMP1; TM4SF10; Transmembrane protein 47; Brain cell membrane protein 1; Transmembrane 4 superfamily member 10 | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, IF, IHC |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Transmembrane protein 47 protein (42-82AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9BQJ4 |
Uniprot Id
Q9BQJ4
Target Species
Human
Target Name
TMEM47
Target Full Name
Transmembrane protein 47
Target Function
Regulates cell junction organization in epithelial cells. May play a role in the transition from adherens junction to tight junction assembly. May regulate F-actin polymerization required for tight junctional localization dynamics and affect the junctional localization of PARD6B. During podocyte differentiation may negatively regulate activity of FYN and subsequently the abundance of nephrin.
Target Subcellular Location
Membrane; Multi-pass membrane protein. Cell junction, adherens junction.
Target Protein Families
TMEM47 family
Target Tissue Specificity
Expressed in adult brain, fetal brain, cerebellum, heart, lung, prostate and thyroid.
Target Synonyms
TMEM47; BCMP1; TM4SF10; Transmembrane protein 47; Brain cell membrane protein 1; Transmembrane 4 superfamily member 10
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