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The antibody against TNFRSF13B was raised in rabbit using the Recombinant Human Tumor necrosis factor receptor superfamily member 13B protein (184-293AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
The antibody against TNFRSF13B was raised in rabbit using the Recombinant Human Tumor necrosis factor receptor superfamily member 13B protein (184-293AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
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Immunohistochemistry of paraffin-embedded human small intestine tissue using TNFRSF13B Antibody at dilution of 1:100
Immunohistochemistry of paraffin-embedded human testis tissue using TNFRSF13B Antibody at dilution of 1:1002
| Cat.No | ADC-44582A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | TNFRSF13B |
| Target Synonyms | TNFRSF13B; TACI; Tumor necrosis factor receptor superfamily member 13B; Transmembrane activator and CAML interactor; CD antigen CD267 | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Antigen affinity purified |
| Conjugate | Non-conjugated | Application | ELISA, IHC |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Tumor necrosis factor receptor superfamily member 13B protein (184-293AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | O14836 |
Uniprot Id
O14836
Target Species
Human
Target Name
TNFRSF13B
Target Full Name
Tumor necrosis factor receptor superfamily member 13B
Target Function
Receptor for TNFSF13/APRIL and TNFSF13B/TALL1/BAFF/BLYS that binds both ligands with similar high affinity. Mediates calcineurin-dependent activation of NF-AT, as well as activation of NF-kappa-B and AP-1. Involved in the stimulation of B- and T-cell function and the regulation of humoral immunity.
Target Involvement
Immunodeficiency, common variable, 2 (CVID2); Immunoglobulin A deficiency 2 (IGAD2)
Target Subcellular Location
Membrane; Single-pass type III membrane protein.
Target Tissue Specificity
Highly expressed in spleen, thymus, small intestine and peripheral blood leukocytes. Expressed in resting B-cells and activated T-cells, but not in resting T-cells.
Target Synonyms
TNFRSF13B; TACI; Tumor necrosis factor receptor superfamily member 13B; Transmembrane activator and CAML interactor; CD antigen CD267
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