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The antibody against TOX3 was raised in rabbit using the Recombinant Human TOX high mobility group box family member 3 protein (8-305AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC, IF.
The antibody against TOX3 was raised in rabbit using the Recombinant Human TOX high mobility group box family member 3 protein (8-305AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC, IF.
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Immunohistochemistry of paraffin-embedded human brain tissue using TOX3 Antibody at dilution of 1:1002
| Cat.No | ADC-15631A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | TOX3 |
| Form | Liquid | Species Reactivity | Human, Mouse |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IF, IHC, WB | Storage | Upon receipt |
| Immunogen Description | Recombinant Human TOX high mobility group box family member 3 protein (8-305AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | O15405 |
Uniprot Id
O15405
Target Species
Human
Target Name
TOX3
Target Full Name
TOX high mobility group box family member 3
Target Function
Transcriptional coactivator of the p300/CBP-mediated transcription complex. Activates transactivation through cAMP response element (CRE) sites. Protects against cell death by inducing antiapoptotic and repressing pro-apoptotic transcripts. Stimulates transcription from the estrogen-responsive or BCL-2 promoters. Required for depolarization-induced transcription activation of the C-FOS promoter in neurons. Associates with chromatin to the estrogen-responsive C3 promoter region.
Target Subcellular Location
Nucleus.
Target Tissue Specificity
Expressed mainly in epithelial cells. Expressed in the central nervous system (CNS), in the ileum and within the brain in the frontal and occipital lobe.
Target Synonyms
BC052044; C230068E13; CAG trinucleotide repeat-containing gene F9 protein; CAGF9; TNRC9; TOX high mobility group box family member 3; TOX3; TOX3_HUMAN; Trinucleotide repeat containing 9; Trinucleotide repeat containing gene 9 protein
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