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The antibody against TPI1 was raised in rabbit using the Recombinant Human Triosephosphate isomerase protein (169-228AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC.
The antibody against TPI1 was raised in rabbit using the Recombinant Human Triosephosphate isomerase protein (169-228AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC.
$299.00
| Cat.No | ADC-13843A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | TPI1 |
| Target Synonyms | TPI1 antibody; TPI antibody; Triosephosphate isomerase antibody; TIM antibody; EC 5.3.1.1 antibody; Methylglyoxal synthase antibody; EC 4.2.3.3 antibody; Triose-phosphate isomerase antibody | Form | Liquid |
| Species Reactivity | Human, Mouse | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, IHC, WB |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Triosephosphate isomerase protein (169-228AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P60174 |
Uniprot Id
P60174
Target Species
Human
Target Name
TPI1
Target Full Name
Triosephosphate isomerase
Target Function
Triosephosphate isomerase is an extremely efficient metabolic enzyme that catalyzes the interconversion between dihydroxyacetone phosphate (DHAP) and D-glyceraldehyde-3-phosphate (G3P) in glycolysis and gluconeogenesis.; It is also responsible for the non-negligible production of methylglyoxal a reactive cytotoxic side-product that modifies and can alter proteins, DNA and lipids.
Target Involvement
Triosephosphate isomerase deficiency (TPID)
Target Subcellular Location
Cytoplasm.
Target Protein Families
Triosephosphate isomerase family
Target Synonyms
TPI1; TPI; Triosephosphate isomerase; TIM; EC 5.3.1.1; Methylglyoxal synthase; EC 4.2.3.3; Triose-phosphate isomerase
Target Background
This gene encodes an enzyme, consisting of two identical proteins, which catalyzes the isomerization of glyceraldehydes 3-phosphate (G3P) and dihydroxy-acetone phosphate (DHAP) in glycolysis and gluconeogenesis. Mutations in this gene are associated with triosephosphate isomerase deficiency. Pseudogenes have been identified on chromosomes 1, 4, 6 and 7. Alternative splicing results in multiple transcript variants.
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