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Rabbit anti-Human TPRKB Polyclonal Antibody

The antibody against TPRKB was raised in rabbit using the Recombinant Human EKC/KEOPS complex subunit TPRKB protein (1-175AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC.

ADC-17676A

The antibody against TPRKB was raised in rabbit using the Recombinant Human EKC/KEOPS complex subunit TPRKB protein (1-175AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC.

$299.00

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Specifications


Cat.No ADC-17676A ClonalityPolyclonal
Host SpeciesRabbitTarget NameTPRKB
FormLiquidSpecies ReactivityHuman
IsotypeIgGStorage Buffer0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4
Purification Method>95%, Protein G purifiedConjugateNon-conjugated
ApplicationELISA, IHC, WBStorageUpon receipt

Immunogen Information


Immunogen DescriptionRecombinant Human EKC/KEOPS complex subunit TPRKB protein (1-175AA)Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ9Y3C4
Background Information
  • Uniprot Id

    Q9Y3C4

  • Target Species

    Human

  • Target Name

    TPRKB

  • Target Full Name

    EKC/KEOPS complex subunit TPRKB

  • Target Function

    Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. TPRKB acts as an allosteric effector that regulates the t(6)A activity of the complex. TPRKB is not required for tRNA modification.

  • Target Subcellular Location

    Cytoplasm, cytosol. Nucleus.

  • Target Protein Families

    CGI121/TPRKB family

  • Target Tissue Specificity

    Widely expressed.

  • Target Synonyms

    CGI 121 ; My019 ; PRPK (p53 related protein kinase) binding protein ; PRPK-binding protein; TP53RK binding protein; TP53RK-binding protein; Tprkb; TPRKB_HUMAN

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