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The antibody against TPRKB was raised in rabbit using the Recombinant Human EKC/KEOPS complex subunit TPRKB protein (1-175AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC.
The antibody against TPRKB was raised in rabbit using the Recombinant Human EKC/KEOPS complex subunit TPRKB protein (1-175AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC.
$299.00
| Cat.No | ADC-17676A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | TPRKB |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IHC, WB | Storage | Upon receipt |
| Immunogen Description | Recombinant Human EKC/KEOPS complex subunit TPRKB protein (1-175AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9Y3C4 |
Uniprot Id
Q9Y3C4
Target Species
Human
Target Name
TPRKB
Target Full Name
EKC/KEOPS complex subunit TPRKB
Target Function
Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. TPRKB acts as an allosteric effector that regulates the t(6)A activity of the complex. TPRKB is not required for tRNA modification.
Target Subcellular Location
Cytoplasm, cytosol. Nucleus.
Target Protein Families
CGI121/TPRKB family
Target Tissue Specificity
Widely expressed.
Target Synonyms
CGI 121 ; My019 ; PRPK (p53 related protein kinase) binding protein ; PRPK-binding protein; TP53RK binding protein; TP53RK-binding protein; Tprkb; TPRKB_HUMAN
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