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Rabbit anti-Human TRABD2B Polyclonal Antibody

The antibody against TRABD2B was raised in rabbit using the Recombinant Human Metalloprotease TIKI2 protein (195-405AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC, IF.

ADC-01545A

The antibody against TRABD2B was raised in rabbit using the Recombinant Human Metalloprotease TIKI2 protein (195-405AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC, IF.

$299.00

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Specifications


Cat.No ADC-01545A ClonalityPolyclonal
Host SpeciesRabbitTarget NameTRABD2B
FormLiquidSpecies ReactivityHuman
IsotypeIgGStorage Buffer0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4
Purification MethodAntigen affinity purifiedConjugateNon-conjugated
ApplicationELISA, IF, IHCStorageUpon receipt

Immunogen Information


Immunogen DescriptionRecombinant Human Metalloprotease TIKI2 protein (195-405AA)Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDA6NFA1
Background Information
  • Uniprot Id

    A6NFA1

  • Target Species

    Human

  • Target Name

    TRABD2B

  • Target Full Name

    Metalloprotease TIKI2

  • Target Function

    Metalloprotease that acts as a negative regulator of the Wnt signaling pathway by mediating the cleavage of the 8 N-terminal residues of a subset of Wnt proteins. Following cleavage, Wnt proteins become oxidized and form large disulfide-bond oligomers, leading to their inactivation. Able to cleave WNT3A, WNT5, but not WNT11. Required for head formation.

  • Target Subcellular Location

    Cell membrane; Single-pass type I membrane protein.

  • Target Protein Families

    TIKI family

  • Target Synonyms

    TRABD2B; HKAT; TIKI2; Metalloprotease TIKI2; EC 3.4.-.-; Heart; kidney and adipose-enriched transmembrane protein homolog; TRAB domain-containing protein 2B

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